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By Trapnell C., Salzberg S. , Last update 1494698999
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tophat-fusion-post description

Tophat-fusion-post produces a list of fusion candidates is given in HTML format. It works in together with tophat-fusion which identifues fusion genes. Fusion genes result from the breakage and re-joining of two different chromosomes, or from rearrangements within a chromosome. Because TopHat-Fusion does not require information about known genes, it can discover novel fusion products from known genes, unknown genes, or unannotated splice variants of known genes.

Parent program: tophat

TopHat is a fast tool for splice junction mapping for RNA-Seq reads. It aligns reads to genome using the high-throughput short read aligner Bowtie, and then analyzes the mapping results to identify splice junctions between exons. It can work without a reference annotation and process mammalian-sized genomes.