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By Bucher P., Last update 1494698998
All tools Run in Terminal

pfw description

Pfw weights sequences of a multiple sequence alignment to correct for sampling bias. pfw computes new weights for individual sequences in a multiple sequence alignment using the method of Sibbald and Argos (1990). The file containing the multiple sequence alignment (*ms_file*) must be either in MSF format as generated by GCG programs or by readseq (checksums are ignored) or in MSA format as produced by psa2msa(1). If *-* is specified instead of a filename, the multiple sequence alignment is read from the standard input. pfw writes a new multiple sequence alignment with modified weights in either MSF or MSA format to the standard output.

Parent program: pftools

PFTools is a collection of programs supporting the generalized profile format and search method of PROSITE.