Htop converts a hidden Markov model (HMM) into an equivalent PROSITE formatted generalized profile. The input hmm_file is a nucleic acid or protein HMM in HMMER ASCII-format. The random_model file contains a simple null-model in the format used by the HMM search programs of the HMMER package. This random model is only effective in conjunction with the -o option (old HMMER format). If omitted, a random model con- sisting of the average residue probabilities of the insert states will be used.
Parent program: pftools
PFTools is a collection of programs supporting the generalized profile format and search method of PROSITE.