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hmmbuild

By Finn R., Eddy S., Last update 1494698999
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hmmbuild description

Hmmbuild constructs profile HMM(s) from multiple sequence alignment(s). Construct profile HMM(s) from multiple sequence alignment(s). For each multiple sequence alignment in build a profile HMM and save it to a new file .


Parent program: hmmer

HMMER software allows search for protein homologs and also permits multiple protein sequence alignment. Unlike BLAST, HMMER uses probabilistic models called profile hidden Markov models which provide a significantly more accurate and more sensitive detection of remote homologs. The HMMER software suite has been widely used, particularly for protein family databases such as Pfam and InterPro and their associated search tools. Also HMMER has several programs for protein sequence analysis such as phmmer, hmmscan, hmmsearch and jackhmmer.