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By Stanke M., Keller O., Morgenstern B., Last update 1494698999
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curve2hints description

Curve2hints makes exon segmentation and grouping the exons together to form the hints for possible position of genes to be used by augustus

Parent program: augustus

AUGUSTUS is a software to predict genes in eukaryotic genomic sequences.The approach is based on a generalized Hidden Markov Model. AUGUSTUS parses a genomic sequence to segments that are most likely according to the underlying statistical models. The program is often the most accurate for ab initio gene prediction for the species it is trained for. AUGUSTUS is able to incorporate EST, mRNA and protein alignments. It also can predict alternative transcripts, splicing and 5'UTR and 3'UTR including introns with probabilities for the transcripts and each exon and intron.