Create-priors takes as input a series of numeric values defined with respect to one or more DNA sequences. The program converts the data into a probabilistic prior. A binned distribution for the priors is also generated. Examples of input data types include sequence tags counts from a DNaseI hypersensitivity or histone modification ChIP-seq assay, or sequence conservation scores.
Parent program: meme
MEME is a tool for discovering motifs in a group of related DNA or protein sequences. MEME takes as input a group of DNA or protein sequences and outputs as many motifs as requested up to a user-specified statistical confidence threshold. MEME uses statistical modeling techniques to automatically choose the best width, number of occurrences, and description for each motif.