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annotate

By Salzberg S., Delcher A., Last update 1494698999
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annotate description

Annotate makes an annotation of the datafile with a gapfile with extra column listing the number of errors counted in each gap of the contigs to reference genome alignment. A gap is defined as an interruption in the MUM-alignment which falls into one of four classes: (1) an SNP interruption, (2) an insertion, (3) a highly polymorphic region or (4) a repeat


Parent program: MUMmer

MUMmer or 'Maximal Unique Matches' is a bioinformatics software system for sequence alignment. It is based on the suffix tree data structure and is one of the fastest and most efficient systems available for this task, enabling it to be applied to very long sequences. It has been widely used for comparing different genomes to one another. In recent years it has become a popular algorithm for comparing genome assemblies to one another, which allows scientists to determine how a genome has changed after adding more DNA sequence or after running a different genome assembly program.